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SOD : multiple applications |
|  The SOD – Super Oxide Dismutase – is a primary antioxidant enzyme, essential to the organism to fight against oxidative effects of free radicals.
This enzyme is naturally present in every living organism. Its presence regulates the formation of peroxidative free radicals, preventing the cell from damage caused by imbalance between the oxidant and antioxidant systems. When this imbalance goes on, it is called oxidative stress.
The SOD – Superoxide Dismutase – strengthens organism’s defences, fights against ageing, increases animals’ vitality, improves their performances and raises their resistance to diseases. It also has a positive impact on meat organoleptic qualities. | |
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Beneficial effects on bovines |
|  To produce milk, a dairy cow has to breed each year. All professionnals are unanimous to acknowledge a lack of immunity at the end of pregnancy and at the beginning of milking, which is improved by an increase of antioxidants (SOD) in feed.
The calf, as any young animal, is totally dependent, in its early days, on antioxidant supplies it has taken after its mother. Its digestive tract is particularly sensitive to beneficial effects of SOD.
Dairy cow breeding still represents a problem encountered by all professionals. The SOD helps implantation of the embryo, which improves breeding. | |
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Beneficial effects on horses |
|  The horse is an emotive animal. This explains why it is weakened during competition periods and so sensitive to stress and gastric ulcers. During these periods, oxidative stress is intense in the competition horse. Its antioxidant needs, especially for SOD, increase. The SOD strengthens resistance to effort.
The horse, whatever it is, a draft horse, a race horse or a show jumper horse, is a very sensitive athlete to tendinous inflammations. These chronic inflammations cause oxidative outbursts sensitive to SOD’s action.
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Beneficial effects on pigs |
|  The pig is a digestive animal par excellence, submitted to intensive feeding which requires high levels of alimentary antioxidants, warranting good organoleptic qualities of the meat. SOD contributes to obtaining this quality. Bred in an intensive way, the pig is submitted to various stresses at each stage of its breeding (weaning, change of food and building, transport, vaccination). Stress generates free radicals. The SOD allows strengthening the resistance to stress.
Breeding is, in the porcine species, the main factor of economical success. The SOD increases the offspring and contributes to strengthen antioxidant pool of the new-borns. | |
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Beneficial effects on poultry |
|  The egg concentrates various nutritive components. The SOD doesn’t escape this rule and concentrates in the egg yolk. It happens during the early moments of the life, providing a balance oxidant/antioxidant. Nothing amazing that this enzyme takes effect on laying performances in poultry farming, on hatching in brooders and on survival of chicks in hen houses.
The SOD is an enzyme of great interest in poultry farming.
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Beneficial effects on dogs and cats |
|  These life companions, as their master, suffer from osteoarthritis, are sensitive to stress, to the pollution caused by traffic in the cities and of course to deleterious effects of ageing. The main origin of these injuries is free radicals, produced in too large quantities to be controlled by the organism of man’s best friend.
That’s why it is essential to supply them with antioxidants, among which the SOD, the first and main antioxidant to prevent their suffering.
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Beneficial effects on aviary birds |
|  These animals, bred in captivity in a human environment, not necessary adapted to them, are sometimes submitted to intense stress. These stresses are responsible for sometimes chronic sudden mortality, with reproduction and behaviour troubles. The performances of the best of them require a high level of health as well as appearance.
The level of food antioxidants is a vital component of that kind of breeding. They are very sensitive animals to SOD deficiency.
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Promutase, the 5 main advantages |  | 1- Promutase 200™ is a vegetal superoxide dismutase whose source is inexhaustible.
The SOD has been known since 1969, this date corresponding to its discovery by Joe Mc Cord and Irwin Fridovitch. But it was produced from bovine red cells. This manufacture was stopped considering the potential danger of animal extracts. The Promutase 200™ SOD exclusively originates from melon whose culture depends on market need, without limitation.
2- Beneficial effects of Promutase 200™ antioxidant suit all animal species.
The Promutase 200™ double protection and the special formulation for animal feeding allow its use with monogastric herbivores (horse) as well as polygastric ones (cow, sheep, goat), caecotrophes (rabbit), rodents (hamster, chinchilla, mouse, rat), omnivores (pig), carnivores (cat, dog), poultry and aviary birds, shrimps and fish.
3- Promutase 200™ is a natural free of OGM guaranteed product.
The melon cultivated to product Promutase 200™ is a natural melon variety not marketed. The whole production is exclusively reserved to the melon SOD use. The control of this melon production provides a perennial supply source and complete tracability over the whole manufacture, allowing a guarantee of GMO-free production.
4- Promutase 200™ is a product easy to use.
It is a raw material adapted to incorporation in animal feed. The product is easily mixed, resists feed manufacturing processes and has a long shelf life.
5- The quality/price ratio is attractive.
The high concentration of SOD (2 600 000 IU / kg) in Promutase 200™ and its production in large quantities allows to market it in a quality / price ratio making Promutase 200™ a very competitive antioxidant source, particularly of melon SOD. |
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Vocabulary | | • Superoxide dismutase
We breathe oxigen to live, which is used by our cells to produce energy. But energy production goes with a low emission of toxic product, as a fire generates smoke. The toxic product is the superoxide anion. It is formed by the addition of one electron, negative electric charge, on molecular oxygen.
The Superoxide dismutase is a natural enzyme of the organism, able to neutralise superoxide anion very quickly.
• Free radicals
These chimical species, produced in our organism, have an odd number of electrons on the external orbital, as the superoxide anion. It gives them the property to react with other molecules by giving them the electron. That is what happens when iron rusts: it gives to air oxygen electrons.
That is why living organisms’ cells rust little by little with ageing, but also strongly in acute diseases or gradually in chronic diseases. Oxygen free radicals are called oxidants for that reason.
• Oxidative stress
Life is like a permanent burning fire. It produces more or less heat for our happiness and let a bit smoke escape, canalized by a good draught of the systems we use. When fire is no more under control, it can either burn everything or suffocate by excessive smoke production. Oxygen free radicals production, the oxidants of the organism, is canalized by the antioxidants’ action. A balance establishes just as in a heartily burning fireplace.
When this balance is disrupted, it is called oxidative stress.
• Enzyme
Numerous chemical reactions are quickened by miscellaneous substances. They are called catalysts. The proteins naturally produced in the living organism and having this property are biological catalysts, called enzymes.
Thus, superoxide anion is naturally knocked down slowly and partially, what gives it time to react with other molecules, causing considerable damage. In the presence of the superoxide dismutase enzyme, superoxide anion is eliminated 10 000 times faster!
• Antioxidant
These molecules are able to neutralize free radicals and to regulate their production. In the best of all possibilities, a balance sets up between oxidants and antioxidants.
The SOD, superoxide dismutase, is a major antioxidant enzyme, the anti-rust enzyme of the organism’s cells. |
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Wrong orthograph | | super oxyde dismutase, superoxyde dismutase, dismmutase, dismutas, dissemutase, oxydant, antioxydant, enzime, oxydatif, radicall, mellon, S.O.D. |
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